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Date: Thu, 26 Nov 2020 13:01:47 GMT
This site compiles COVID-19 genetic scan results for immediate public download and use from any source permitting such use. Right click links provided here and select “open link in a new tab” to stay on this webpage.
Prior to 07/14/2020: The use of the term “positive” below denotes a positive or assumed positive COVID-19 case based on study definitions. “Negative” indicates someone who has tested negative or presumed negative based on study definitions for COVID-19.
“Unknown” indicates population control samples who may not have been tested or may not yet have results.
Between 07/14/2020 and 09/08/2020: COVID-19 deaths (CD 10 U071) or inpatient diagnosis of COVID-19 (ICD 10 U071) were also added to “positive”. When new death data are released by UK BioBank, six COVID-19 death GWAS will be conducted in addition to COVID-19 GWAS.
From 10/16/2020 and on: COVID-19 deaths (ICD 10 U071), inpatient diagnosis of COVID-19 (ICD 10 U071), primary care clinical data (both TPP/CTV3 and EMIS/SNOMED CT coding systems – see below) were also added to “positive”.
COVID-19 in TPP/CTV3 coding system (01/31/2020 or later)
Y228d: Coronavirus disease 19 caused by severe acute respiratory syndrome coronavirus 2 confirmed by laboratory test (situation)
Y20d1: Severe acute respiratory syndrome coronavirus 2 detected (finding)
Y20fa: Coronavirus disease 19 caused by severe acute respiratory syndrome coronavirus 2 (disorder)
Y210a: Pneumonia caused by severe acute respiratory syndrome coronavirus 2 (disorder)
Y210b: Infection of upper respiratory tract caused by severe acute respiratory syndrome coronavirus 2 (disorder)
Y210e: Detection of severe acute respiratory syndrome coronavirus 2 using polymerase chain reaction technique (procedure)
Y23f7: SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) detection result positive
COVID-19 in EMIS/SNOMED CT coding system (01/31/2020 or later)
EMISNQCO303: 2019-nCoV (Wuhan) infection
186747009: Coronavirus infection (disorder)
12802201000006101: Confirmed 2019-nCoV (novel coronavirus) infection
1240581000000104: 2019-nCoV (novel coronavirus) detected
1300721000000109: Coronavirus disease 19 caused by severe acute respiratory syndrome coronavirus 2 confirmed by laboratory test (situation)
1240751000000100: Disease caused by 2019-nCoV (novel coronavirus)
1240561000000108: Encephalopathy caused by 2019-nCoV (novel coronavirus)
1240571000000101: Gastroenteritis caused by 2019-nCoV (novel coronavirus)
1240531000000103: Myocarditis caused by 2019-nCoV (novel coronavirus)
1240521000000100: Otitis media caused by 2019-nCoV (novel coronavirus)
1240551000000105: Pneumonia caused by 2019-nCoV (novel coronavirus)
1240541000000107: Upper respiratory tract infection caused by 2019-nCoV (novel coronavirus)
1240511000000106: Detection of 2019-nCoV (novel coronavirus) using polymerase chain reaction technique
1240381000000105: Severe acute respiratory syndrome coronavirus 2 (organism)
From 11/03/2020 and on: We added hospitalized COVID-19 GWAS and severe COVID-19 GWAS with primary care data (both TPP and EMIS) being released by UKBB. A hospitalized COVID-19 case is defined by a sample with inpatient diagnosis of
COVID-19 (ICD 10 U071). A severe COVID-19 case is defined by a sample with COVID-19 death (ICD 10 U071) or with inpatient diagnosis of both COVID-19 and dependence on respirator (ICD 10 Z991 and Z9911) in the same instance index, or
a COVID-10 case with advanced respiratory support (from inpatient critical care data). Due to limited case samples, currently we only conducted both hospitalized and sever COVID-19 GWAS for European and overall samples in UKBB – with
3 additional non-European GWAS for hospitalized COVID-19.
After each COVID-19 release of UK Biobank data (门禁市场现状：安防网络化下需开放融合) we are calculating GWAS summary statistics and releasing them to this site.
Summary statistics are for UK Biobank (v.3) imputed genome-wide association (GWAS) studies of COVID-19 test positives with variant filters of imputation quality INFO score >0.3,
minor allele count (MAC) > 2, minor allele frequency > 0.0001.
Note allele2 is coded allele.
See SAIGE output description here: For now, most of the activity around bitcoin is monetary in nature, so it makes sense that its critics point to volatility. Though the value of one bitcoin in U.S. dollars has fallen 67% in the past year, its value over the past two years is up 1,879%, according to the market price chart at blockchain.info. So whether it’s a good investment or a bad one is a matter of perspective..
Ellinghaus, Degenhardt et al.
Meta-analysis of Spanish and Italian COVID19 cases with respiratory failure
NOTE: full GWAS files are GRCh38 build position whereas top results and annotated files have been Lifted Over to GRCh37.
COVID-19 Host Genetics initiative results provided under Creative Commons License. This includes meta-analyses of international case/control samples with a larger sample size than UKBB alone. These analyses may also have greater test/population ascertainment and genetic heterogeneity effects. If you have samples to contribute we urge you to consider joining.
See also 房企新“王”加冕 保位谋多元化转型？ and 全国住建工作会议为2018年房地产发展指明方向
All files are in compressed Gzip format.
Send questions, comments or requests to add data or analysis to: firstname.lastname@example.org, email@example.com,