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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

8月份,Facebook首席执行官马克扎克伯格说:“我们认为这对我们国家的未来真的很重要。”
Denmark, Norway, Switzerland, the Netherlands and Sweden are the world's happiest countries, according to the survey of 156 countries. Rwanda, Burundi, the Central African Republic, Benin and Togo -- all nations in Sub-Saharan Africa -- are the least satisfied with their lives, the report said. China ranks 93rd in the list.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

This year they looked at the use of negative strategies such as anger or stonewalling responses to conflict, and found that these predicted health-related changes over time in specific ways.
《我们这一天/我们的生活》

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

如果现在的闪电侠韦德减掉30磅肌肉,那你可能就分不清NBA版和高中版的韦德了。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

每一次我们詹姆斯已经达到了顶点,詹姆斯就会拿出更好的表现超过那个顶点。他那无所不包的各项技巧,是詹姆斯辛苦训练的证明。你可以嘲笑他所提发布的所有Instagram录像,但这些都是他仍然能够做到这一点的真正原因;詹姆斯从来不轻视他的每一场比赛,一次都没有。结果便是晚上一次又一次无可比拟的表演。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

按照我们过去三年的观察,感恩节旅游季期间的航班晚点率实际上有所下降——据美国交通运输部的数据显示,去年感恩节航班的晚点率仅为12%,低于2010年的19%。
['treidmɑ:k]
The economy will grow 3% for the first time in 10 years
久而久之,这种民族融合给球队带了不同寻常的和谐。队中的年轻球员,尤其是切尔西的阿扎尔和卢卡库以及曼联的贾努扎伊,成了许多竞争对手羡慕的对象。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

Magic show (Lu Chen)
Thus assuming that type D personalities lack social interest is not correct but the right thing is that they might be interested in people but afraid to approach them because they fear rejection.
Foreign investment in emerging markets has dropped to the lowest level since the financial crisis as investors are braced for the fallout of the first US interest rate rise in nearly a decade.
这是中国首次占据榜单前三甲以及在前10强中占了5名。中国工商银行连续两年占据第1名的宝座,中国建设银行次之,而且中国农业银行向上移动了5名成为第3名。这三大银行与排在第9名的中国银行一起跻身前10强,中国银行是“四大国有银行”中的另一个成员。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

As he scanned the Internet for knowledge, D'Aloisio decided that what he really needed was a better way to determine, at a glance, what was worth reading. He envisioned a summarization tool that used language theory to give a meaningful synopsis in fewer than 400 characters.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

这个领域的创新速度非常快。自从Fitbit于2008年成立以来,各家公司已经发布了五到六个完全不同的产品。三星(Samsung)则在九个月内发布了可穿戴设备Galaxy Gear的三到四个衍生产品。索尼(Sony)、Pebble、谷歌和Facebook的头戴式虚拟现实设备Oculus Rift也紧随其后。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

The job market faces challenges. Some five million Americans have been out of work for six months, raising the risk their skills will erode and make it even harder for them to find jobs down the road. And fears of slowing revenue growth could keep a lid on hiring by companies. About 36% of U.S. executives expect the head count at their firm to fall, according to an October survey by advisory firm CEB, compared with 29% who said that during the summer.[qh]
埃尔·南德斯

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

spread
国家统计局高级统计师绳国庆将这一下滑主要归因于食品价格下降了1.4%,这是15年来的首次下降。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 房地产市场乱象当严治
Open Access Review Article

Diagnostic technologies for COVID-19: a review

莱昂纳多·迪卡普里奥和嘎嘎小姐在今年金球奖拔得头筹。
addition

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

pollution
7.《大白鲨》
It is up to other institutions — notably, Congress, courts and media — and the citizens at large now to do so.
We will speed up the reform of SOEs and state capital.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

经济大萧条在全美各地产生了破坏性的影响,然而很少有地区像亚利桑那州那样遭受重创。20世纪初,该州借助强大的旅游业和房地产市场蓬勃发展。住房中位数价格在2003年到2006年间上涨了70%——仅次于内华达州的增幅——带动了更多的房屋和建筑行业工作岗位。直到2007年接近年底的时候,亚利桑那州的月失业率都一直维持在3.5%的低水平。但是随后经济陷入低谷。住房价格从相比高点惨遭腰斩,亚利桑那州6%的房产在2009年收到了止赎通知。在2009年和2010年的大部分时间里,该州的失业率保持在两位数居高不下,从最近五年的失业率情况看,恶劣程度仅次于内华达州。2008年以来,该州的家庭收入以全美最快的速度下降。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Bolder lawyers will start working with more “sci-fi” programs that claim to predict the outcomes of legal disputes before they have reached court, by analysing similar cases and past rulings, opposition tactics and win/lose statistics, the success rates of certain lawyers before certain judges, and so on.
3. Not starting your own business

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 广州“自愿不购买社保”条款无效
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

多数天主教徒(60%)和非福音派白人新教徒(65%)表示,他们相信飓风和洪灾等自然灾害是气候变化所致。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Federal, state and local government job cutbacks are slowing. More than 250,000 workers at all levels of government lost jobs last year. This year, so far, about 20,000 have gained jobs. Worries about the nation's debt and deficits likely will keep a lid on government spending and investments, economists say, but any jumps in, say, infrastructure spending would create jobs. At the least, government will be less of a drag.[qh]

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 家具:进口价格不敌代购
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

五大发展理念:创新、协调、绿色、开放、共享的发展理念
陶博宏表示,这可能过于悲观了。他说:“亚洲的情况往往比我们想象的更快变化。”
谎言8:我写了5页的简历,那是因为我足够好。说谎原因:我就是个不折不扣的话唠!
Farewell to Don and his perfect suits, to Peggy and her plaids, to Joan and her jewel tones and sheaths.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

6.The Stock Market Plunge
Even though we are apart, you are in my heart this season.千山万水,隔不断我在佳节对你的思念。
Online registration will end on Oct. 24. The exam will be held on Nov. 27 in major Chinese cities.
或许这种做法不会在竞争激烈的华尔街推广。有人可能会认为,长时间的休假相当于承认他们的工作可有可无,即使没有他们,同事们也可以生存,或许更能发挥才华。
But only 14,000 tourists took advantage of the visa-free stopover, according to the Beijing General Station of Exit and Entry Frontier Inspection, well short of the 20,000 target officials had previously predicted.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

a不,非,mnes记忆-不记仇-赦免
1999:H9N2传染人类1999: H9N2 Infects Humans

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

腾讯通过聊天软件QQ的渠道将用户吸引到它的网络游戏和网站上去。分析师说,类似的模式对于微信也有可能非常管用。他们也说,微信的“朋友圈”功能给它加进了社交网络的元素,有可能最终吸引到广告商。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

单词turkey 联想记忆:

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Mr Na said that although South Korea had signed a trade agreement with China, there were plenty of other ways in which Beijing could punish Seoul.
In March, Ford completed its exit from the luxury car market by selling Volvo to China's Geely Automobile for $1.6 billion. Although the sale represents a sharp loss - the company paid $6 billion for the Swedish automaker eleven years ago - Ford posted an annual profit of $2.7 billion in 2009, its first profitable year since 2005. Assisted by the 'Cash for Clunkers' program (not to mention Toyota's accelerator woes), Ford recaptured its position as the nation's largest carmaker in February. Which is why Ford's CEO Alan Mulally can now look abroad, including big markets like India, where it recently introduced the compact Figo.
7. 《出局:禁止接触》(Out 1: Noli Me Tangere),导演:雅克·里维特(Jacques Rivette)。
19. 前进直至消失。昆汀·塔伦蒂诺(Quentin Trantino)用70毫米胶片拍摄了新片《八恶人》(The Hateful Eight),这部影片将在将近100家影院上映,它们和全国大多数影院一样,通常使用数码放映。不管你对塔伦蒂诺有何看法,你都应该去影院看《八恶人》,这样你就可以自己看看,这个行业被迫转向数码,对电影究竟产生了多大的影响。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

剧烈动荡石油产量—随着更加缓慢增长的世界经济—造成了原油价格从2013年100美元一桶到2014年年末的几乎50美元一桶的大幅下降,而在美国国内2014年初却造成了通货膨胀的相反影响
The board is frequently covered in equations. Have you ever wondered what those equations mean? Well, we may never know what they mean, but they are all real, accurate equations. Very impressive, Big Bang. Very impressive indeed.
随着新款iPhone不断刷新自己的发售纪录,库克推出了Apple Watch和Apple Pay等产品,引领苹果进入时尚界和金融界,让这家公司再度焕发出许多人担心已和乔布斯一同逝去的创新精神。苹果今年一年市值的增长,就接近谷歌(Google)的整体市值。
Chinese insurers saw their profits implode in the first six months of 2016.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

为了尝试遏制煤炭消耗量的增长,中国正在可再生能源和核能领域投入巨资,但尽管付出了这些努力,中国迄今为止依然是最大的温室气体排放国。中国每年因化石燃料燃烧和水泥生产排放100亿吨二氧化碳,几乎是美国的两倍,但美国的人均排放量依然远远高于中国。
一份新发布的研究表明,2014年,全球药品支出将超过万亿美元,治疗丙型肝炎和癌症的创新药品为高价药。截至2018年,预计药品支出费用将再提高三成。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

One suggested change: require rent-stabilized tenants to verify their income.
The EU’s Americas gambits
商务部本月早些时候表示,消费品的零售销售是去年消费的一项关键指标。该销售额同比增长了10.7%,占去年全国66.4%的GDP增长。
n. 罪犯
A review of our work in 2016

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 土地估价机构9月底前需完成备案
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

简言之,2014年种种相反的趋势无法描述和解释。我也不信,多年之后,人们凭借后见之明,能将今年发生的种种事情看得更清楚。
They are calculated using a methodology that focuses on a school's research performance and reputation, not its specific undergraduate or graduate programs. This is a separate methodology than those used for other US News rankings such as Best Colleges and Best Graduate Schools.
哥伦布日在1971年成为美国假日。银行、州政府办公室、邮局和联邦机构都会放假。债券市场休市,但许多商家和股票交易所继续开放。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Spending on medicines in "pharmergingmarkets" will rise more than 50 percent over the next five years, ThePharma Letter said, citing IMS.
There is still tremendous untapped potential in China-Russia economic and trade ties and the two economies are highly complementary. The goals set for the two-way trade can be achieved.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 陶瓷卫浴市场六大黑幕令人忧
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 未来已来,新工具赋能城市新时代
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

“This is not an excuse — this is the reality of the environment we operate in, ” Dervin said. Since 2012, JetBlue has been implementing a series of technology efforts to help it recover more quickly from bad weather. She said other tools are coming online that will help the airline keep to its schedules.
我的核心价值观是什么?作为一个人,对你来说什么是重要的?家庭、健康、信仰、工作还是其他?确保在你的生活中,你追寻了自己最在乎的东西。
Eleven James:

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

到了明年3月,这些明日之星中很有可能会有1-2个人脱颖而出,可以成为球队基石。
"Last year, 1.2 million Chinese visited Australia. We anticipate this will grow during the China-Australia Year of Tourism and will continue to grow afterward."
尽管这笔节省下来的钱目前看来相当可观,但其实远不够填补随之而来的不断升高的患病率所增加的社会负担的窟窿。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

加拿大城市温哥华依然是北美地区最贵城市,在生活成本指数榜单上名列第21位。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

My arms are wide open for you this New Year.我张开双臂,盼与你共度新春佳节。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Kobe Bryant really hasn't changed that much since high school, even though it's been 16 years since he's walked the halls of Lower Merion High School.
While the FT online and full-time MBAs are not strictly comparable because the criteria used to judge them are slightly different, it is interesting to note that IE and Warwick Business School are among six schools to feature in both rankings.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Until a couple of games ago, Stephen Curry really hadn't thought much about making more NBA history.
5.Effective decision makers
回购股票会帮助推高股价,很多分析师将标准普尔500(Standard & Poor's 500 index)创下多次历史新高归功于股票回购的盛行。
最佳轿车品牌:马自达

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Other notable custom course performances include Harvard Business School, which recorded one of the year’s biggest rises, jumping nine places to fifth. The Massachusetts school was ranked 18th two years ago.
"My hair has turned white, half because of housing prices and half because of you reporters." JIANG WEIXIN, member of the CPPCC National Committee and minister of housing and urban-rural development, responding to media questions about government measures to curb housing prices

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

The three bubbles: The Asian Bubble in the early '90s, Dot-com Bubble of the late '90s and what Juckes calls the Great Big Credit Bubble that triggered the 2008 Wall Street meltdown.
指数: 97.8

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

养老保险基金收不抵支的省份正在增多。作为去年养老保险基金入不敷出的6个省份之一,黑龙江的企业养老保险可支付月数最多仅为1个月。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

TOP SONGS
The relocation is also part of the integration plan for the Beijing-Tianjin-Hebei cluster, which aims to ease congestion in the capital and achieve more balanced development in the region.
不过,日本央行(BoJ)仍决定不加大货币政策刺激力度。该行指出,工业产出是日本经济疲软的领域之一。当然,就业市场等日本经济的其他领域,表现要好得多。
这种现象部分原因可能来自人民币汇率总体的疲软,原因是这会令境外的商品变得更加昂贵。今年1月人民币汇率下跌了1.3%,而在2015年最后一个季度人民币贬值了2.2%。不过,中国的出口仍未因人民币贬值而受到提振。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

Metals cases made up a record 46 per cent of the 233 anti-dumping actions brought worldwide in 2015, with the steel industry accounting for almost all of the metals complaints.
据中国海关总署公布的统计数据显示,2016年中德外贸总额达到了9991亿元人民币(约合1453亿美元),同比2015年增长了2.6个百分点。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Armistice Day became an official U.S. holiday in 1938, and remained so until 1954, when it was renamed Veterans Day in the aftermath of both World War Two and the Korean War. It is separate from Memorial Day, which is observed on the last Monday in May and honors servicemen and women killed in war.
This post is in partnership with Entrepreneur. The article below was originally published atEntrepreneur.com.
现在似乎可以放心地预言,2017年余下时间会出现更多噪音、甚少进展,而这将继续对贸易和英国经济造成破坏。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Epic Games在网站Kotaku上发表的一份声明中则指出,提起法律诉讼的原因是罗杰斯在一个YouTube视频的可移除标签上写下了涉及DMCA的反诉内容,这段视频展示并推广了《堡垒之夜》外挂软件。
而90后微信用户数量则略有下降,从94.1%跌到了86.6%。
答:其实我并不怎么关心作品火不火的,就是专注于自己的作品而已。每次我关注的就是要怎样用最好地推进剧情而已。我关注的是行为和故事,不是受欢迎程度。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

姚振华在收购中国最大房地产商万科股份的竞争中引起了关注。
n. 生存,幸存者

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 广西推出印章管理10条便民举措
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

“Why did this happen to my daughter?” she said. “There’s been so many deaths because of the guns. I don’t know how many people have to die.”
The group’s leader, Wang Rongzhen, told Reuters on Wednesday that the automaker has scaled back the range of models it supplies to dealers in Hyundai imports in China, only consistently supplying one model, while steadily increasing car manufacturing in China.
这份排行榜基于对商学院及其2013届毕业生的调查。根据校友职业发展、学校创意生成以及学员和师资多样化对MBA课程进行评比。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 2015年全球办公室LED照明收入逾12亿
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

第一架无线电操纵的无人驾驶飞机可追溯到1916年。英国发明家阿奇博尔德·洛设计并试飞了第一架无人遥控飞机。它是为了反攻德国齐柏林飞艇而制作的,在第一次世界大战中参与了对地面攻击的战斗。无人机由木和锡制成,它的机翼用的是其他双翼飞机的较低机翼。总的来说,无人机是有些失败的,因为它的引擎噪音干扰了无线操作。1916年,索普威斯飞松公司也尝试制作无人机,他们将无线电设备放置在无人机的尾部,这样引擎就不会干扰到它的信号。但因一次地面上的意外事故,他们的无人机再未起飞:当洛操作无人机飞到高级军官面前时,他原本计划会在1917年再次试飞无人机。但无人机从卡车的后面发射后,飞了一段时间便因引擎故障而坠毁,差点要了在场的军官的命。
This groundbreaking fight is loosely based on a bout between Chuck Wepner and Muhammad Ali, in which the "everyman" Wepner managed to become one of the four men to knock Ali down in his career. Just like in the film, Wepner pushed Ali through 15 rounds despite looking (and feeling) like he'd been hit by a truck. While both he and Rocky ended up losing their fights on a technicality, Wepner wins in our book for inspiring such an awesome character.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 广州“自愿不购买社保”条款无效
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

neglect
年度故事将是纽约对911主谋穆罕默德(Khalid Sheikh Mohammed)的审判。
当前油价正在发生什么变化?在业内人士和严肃的投资者中间,对这个问题有两种不同的看法。2016年油价走势或许有助我们看清哪种观点是正确的。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Welcome, and before we begin – please accept our apologies. Your four-hour nightmare wait at passport control should not be taken as a symptom of Britain's contempt for foreigners. It is merely a symptom of a woeful lack of spending on a key aspect of travel infrastructure in the run-up to a hugely important event. In other words, it's the government that hates you. Don't worry, they hate us too.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

中国和越南的关系因中国南海领土问题而变得日益紧张。两国媒体都对这一事件进行了报道,指责各自政府将非法食品投放本国市场。
而在非手术整形中,注射肉毒杆菌和激光脱毛依然是最受欢迎的。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 家居上市企业中报8月密集披露
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

The June announcement of collaboration between Google and fashion designer Diane von Furstenberg to create a new line of Google Glass underscored Silicon Valley’s current strategy to enlist the fashion elite to sanction wearables as de rigueur.
价格:205万美元(约合人民币1312万元)

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

同时,大批与比特币相关的创业公司于2014年创建,表明比特币势头强劲。我们没有比特币新创企业的详尽名单,但几乎可以肯定的是,2014年成立的比特币新创企业的数量,高于此前任何年份。融资平台AngelList发给《财富》的数据证实了这一点。2011年,5家比特币初创公司在AngelList上登记。2012年,这个数字增加到13家;2013年跃升至193家;2014年更是暴增至566家。【但并非所有创业公司都会(立即)在AngelList上登记。】此外,正如巴里o希尔伯特在推特上所言,1月8日,比特币日交易总量创下历史新高。
Less than an hour ago the official manufacturing PMI for November came in at 49.6, the fourth consecutive month of contraction and below the 49.8 reading economists were looking for. Analysts at ANZ said, in relation to that PMI series:“With soft growth momentum and deflation pressures creeping up, we expect the authorities to further ease monetary policy and continue to implement an expansionary fiscal policy in order to prevent further slowdown of the economy in 2016.”

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

别人可能会告诉你“在面试中展示真正的自我。” 但是,真的别随便展示。这是最烂的一条建议。我们不需要一些神经古怪的人,我们关心的只有你的的技术和经验。
corn

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

她还表示,从较长期来看,另一个让她担心的“R”是“重置”(reset),她解释称,全球各地的货币和财政政策在回归正常之前还有很长的路要走。她补充称:“最终的重置是那些在全球各地都有必要实施的结构性改革。”

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

But the struggle for white identity is not just a political problem; it is about the “deep story” of feeling stuck while others move forward.
Indeed, everyone from Jennifer Garner, to January Jones and Kylie Jenner have been photographed as they pick out their most spook-worthy pumpkins in time to send October out with a thrill.
It was not an auspicious start to the new year for bitcoin investors.
What would he try for his solo move: "Sweet Creature" and "Ever Since New York" are intimate acoustic ballads; while "Kiwi" lets him strut his Oasis-style self at top volume. "Two Ghosts" is a break-up lament .

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

IT/通信/电子/互联网行业的应届生签约最高月薪为4867元,同比去年下降826元;紧随其后的是金融业和交通/运输/物流/仓储行业,平均签约月薪分别是4692元和4457元。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

500富人榜中20%的富豪来自信息技术行业,而资产投资者正逐渐淡出该榜单。
美国太空探索技术公司取得了一项令人难以置信的成就。“猎鹰9号”发射器的一级火箭在成功将货物运送到国际空间站后,能够自主转向,释放了主发动机燃烧提供的巨大动能,飞回地球并垂直降落在漂浮在大西洋上的一艘相当小的自动驳船上,极其精准。
一份调查报告称,2014届中国大学毕业生的就业满意度为61%。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Star risers
乔布斯正在展示 iPad 2。2011年3月,旧金山

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Awards: Despite early wins for VW’s Golf GTI, the Detroit-centric jurors of the North American Car and Truck award 2015 prizes to Ford’s Mustang as well as Ford’s F-150 pickup truck.
三个泡沫分别是:20世纪90年代初的亚洲泡沫,90年代晚期的互联网泡沫,以及在2008年引起华尔街崩盘的那次泡沫,朱克斯称之为“信贷大泡沫”(Great Big Credit Bubble)。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Dafoe is probably the current front runner for best supporting actor.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

China will remain an important engine for world growth amid sluggish global economic recovery.
中国房价在今年初曾以9.6%的同比增速快速上涨,但此后随着经济放缓以及很多中等规模城市遭遇房产供应过剩,房价一直在下跌。
?在纽约的交通基础设施遭受巨大的打击。许多城市的地铁隧道被淹没。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Negative emotions such as worrying, stress, depression and anger visit type D personalities more often. A small event that is usually overlooked by others can bother a type D a lot and even ruin his mood.
Shipments of cellphones made by Chinese companies reached 498 million in 2016, accounting for 88.9% of the country's total shipments, according to the report from the China Academy of Information and Communication Technology.
是的,你想知道怎么去做好你的工作。但是仍然有一些你想要学的东西;否则,你就没有职业发展。如果你在工作中不能学到新的东西,那么已经是时候去找一个能够学到新知识并且有职业发展的工作了。
Ladies and gentlemen, may I welcome you to the Bad Manners Awards 2016?

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Three Billboards Outside Ebbing, Missouri is a darkly comic drama from Academy Award winner Martin McDonagh.
Nothing else matters, not even basic astronomy.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

PwC has counted votes and provides winner envelopes for the Oscars and has done so for more than 80 years. This is the first time in Oscar history that the wrong envelope had been opened while an award was being announced.
Lots of managers recalled extreme etiquette errors. The applicant
n. 摘要

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 12月 年底楼市平稳“收官”
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1月,因本田未按要求向美国国家公路交通安全管理局汇报各类车辆上发生的1700多起伤亡事故,美国政府向该公司开具7000万美元的高额罚单。
Originally intended for the opening credits of Tomorrow Never Dies, and then for some reason relegated to the closing credits, K.D. Lang's "Surrender" is silken and cool. The horn sections are sassy and powerful. It's one of the best James Bond theme songs, and it's not even officially a James Bond theme song. And it's a heck of a lot better than the official theme the movie finally got.

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